ODCs

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1 OMIM reference -
1 associated gene
No signs/symptoms info

PROTEIN INTERACTIONS: 1

2 OMIM references -
2 associated genes
3 signs/symptoms

Anhidrotic ectodermal dysplasia - immunodeficiency - osteopetrosis - lymphedema

Hypomyelination - hypogonadotropic hypogonadism - hypodontia

IKBKG	(UniProt - OMIM)		POLR3A	(UniProt - OMIM)
			POLR3B	(UniProt - OMIM)


INTERACTOME ASSOCIATIONS (click on a score value to see the evidence)	IKBKG	(0.63)	POLR3A

Citations in the biomedical literature:

Anhidrotic ectodermal dysplasia - immunodeficiency - osteopetrosis - lymphedema		Hypomyelination - hypogonadotropic hypogonadism - hypodontia
	Synonym(s): - OL-EDA-ID		Synonym(s): - 4H syndrome

	Classification (Orphanet): - Rare bone disease - Rare circulatory system disease - Rare developmental defect during embryogenesis - Rare genetic disease - Rare immune disease - Rare skin disease		Classification (Orphanet): - Rare endocrine disease - Rare genetic disease - Rare gynecologic or obstetric disease - Rare infertility - Rare neurologic disease

	Classification (ICD10): - Congenital malformations, deformations and chromosomal abnormalities -		Classification (ICD10): - Diseases of the digestive system -

	Epidemiological data: Class of prevalence: <1 / 1 000 000 Average age onset: neonatal/infancy Average age of death: before age 5 Type of inheritance: x-linked recessive		Epidemiological data: Class of prevalence: <1 / 1 000 000 Average age onset: adolescence / young Average age of death: - Type of inheritance: autosomal recessive

	External references: 1 OMIM reference - No MeSH references		External references: 2 OMIM references - No MeSH references

Hypomyelination - hypogonadotropic hypogonadism - hypodontia
	Very frequent - Anomalies of teeth and dentition - Ataxia / incoordination / trouble of the equilibrium - Late puberty / hypogonadism / hypogenitalism
Anhidrotic ectodermal dysplasia - immunodeficiency - osteopetrosis - lymphedema
(no data available)